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Nov 03, 2025Exploring the Pathogenesis of Allergic Rhinitis and Transgenic Mouse ModelsAllergic rhinitis (AR), also known as hay fever, is a common chronic inflammatory disease of the upper respiratory tract. Its typical symptoms include rhinorrhea (runny nose), nasal congestion, nasal itching, and repeated sneezing. It is estimated that over 500 million people worldwide are affected by allergic rhinitis. In China, the prevalence of allergic rhinitis among adults is as high as 17.6%, and this number has increased significantly over the past six years. -
Aug 21, 2025Industry Outlook | First Personalized Base Editing Therapy Successfully Treats Rare Genetic Disease, Developed in Just 6 MonthsOn May 15, 2025, a research team from the Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania published a landmark study in the New England Journal of Medicine(NEJM): the first successful application of a bespoke gene-editing therapy, developed for a single patient, to treat an infant with a rare and fatal genetic disorder—carbamoyl phosphate synthetase 1 (CPS1) deficiency. -
Aug 21, 2025TRIM11 Emerges as a Promising Novel Therapeutic Target for Alzheimer’s DiseaseAlzheimer’s disease is a progressive neurodegenerative disorder characterized by a gradual decline in cognitive function, including memory loss, impaired thinking, and behavioral changes. The disease is strongly associated with aging and is most commonly observed in individuals over the age of 65.

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