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MingCelerHumanized Models
Gene-humanized mouse models (also known as knock-in humanized models) are genetically engineered mice in which a specific mouse gene has been replaced with its human counterpart. This precise genetic substitution allows the mouse to express the fully functional human protein in its normal physiological context, creating a powerful in vivosystem for studying human biology and testing therapeutics targeting human-specific molecules.
Studying the unique function and regulation of human proteins that may not be fully conserved in mice.Investigating the role of human-specific genetic variants or mutations in disease pathogenesis.
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Immunology ResearchnuNPG Immunodeficient MiceApplicationHuman cell or tissue transplantation；
Hematopoietic and immunological studies；
Cancer and Cancer Stem Cell Research；
Human Disease Infection Models Research；FeaturesMost severely immunodeficient tool mouse model available worldwide；
No residual Prkdc expression；
Tumor formation with minimal cell input (cell line/type-dependent)；Learn more -
Cancer immunotherapy and autoimmune disease researchTIGIT Humanized MiceApplicationEfficacy evaluation of TIGIT inhibitors；
Cancer immunotherapy and autoimmune disease research；
TIGIT Antibody Safety Profile；
Immunomodulatory Mechanisms of TIGIT Targeting；FeaturesMimics human immune responses；
Ideal for drug development and evaluation；
Compatible with diverse cell type studies。Learn more -
Lipid-Lowering DrugsPCSK9 Humanized MouseApplicationCardiovascular disease research；
Screening and evaluation of humanized PCSK9 antibodies；FeaturesPrecisely mimics human gene expression patterns；
Meets specific targeted therapy research needsLearn more -
Endogenous ResearchACE2 Humanized MouseApplicationDrug DevelopmentFeaturesHumanized ACE2 expression patterns and levels closely resemble endogenous biology.
The most compatible and cost-effective animal model for coronavirus research.Learn more -
Hypertension ResearcheNOS Mutant Hypertensive Mouse ModelApplicationHypertension ResearchFeaturesSuccessfully recapitulates human essential hypertension pathology
Enables study of comorbid conditions in populations with pre-existing hypertensive disordersLearn more
Our advantages
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Rapid Production Without BreedingAchieve homozygous F0 mice in 2 months -
Unmatched Capacity for Complex Models100 kb knock-ins, Mb-range deletions, multi-target gene editing. -
3R-Compliant ArchivingCryopreserved ES Cell Bank of gene targeted mice – Zero Genetic Drift,3R-Compliant Archiving, Free 2-year cry storage of validated ES clones. -
"Clone Factory""Clone Factory" Mass Production: Unlimited expansion of gene-edited ES cells for mass production of the homozygous/multi gene edited mice.
Online Quotation
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We offer tailored gene editing solutions—get a free quote instantly.
Fill out the form, and we will contact you within two business days.
Alternatively, call us at 400-8388-113 or reach technical support at 18126776342 (also available on WeChat).
Fill out the form, and we will contact you within two business days.
Alternatively, call us at 400-8388-113 or reach technical support at 18126776342 (also available on WeChat).
