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MingCelerKO/CKO Mice
Knockout (KO) Mice are genetically engineered animal models in which a specific target gene has been permanently inactivated or "knocked out." This allows researchers to study the function of the gene by observing the phenotypic consequences of its absence.
To determine the fundamental biological role of a gene by studying the developmental, physiological, or behavioral abnormalities that result from its loss.
Conditional Knockout (CKO) Mice represent a more advanced version of this technology. In CKO mice, the target gene is flanked by specific DNA sequences (most commonly loxP sites). The gene remains functional until it is specifically deleted by the presence of an enzyme called Cre recombinase. This allows for precise control over where(in which tissue or cell type) and when(at which developmental stage) the gene is inactivated.
To study the role of a gene in a specific organ (e.g., liver, brain) without affecting other tissues, which is crucial when a whole-body knockout is lethal during embryonic development.
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Fill out the form, and we will contact you within two business days.
Alternatively, call us at 400-8388-113 or reach technical support at 18126776342 (also available on WeChat).
