The lab is about to bring in a new batch of mice. What are the common infectious diseases in mice? Common infectious diseases in laboratory mice mainly include bacterial/viral diseases and parasitic infections. Let's discuss them in detail.

1. Definition of Immunodeficient Mice Immunodeficient mice refer to mice with compromised immune function, resulting from congenital genetic defects or deliberate artificial methods. They serve as essential tools for modern medical research. Humanized immunodeficient mice specifically refer to mice carrying human functional genes, cells, or tissues. The establishment of humanized mouse models provides new options for studying human diseases. These models typically serve as in vivo surrogate systems for investigating human diseases, offering significant advantages and broad application prospects in elucidating pathogenesis mechanisms and drug screening.

Is your gene-edited mouse breeding inefficient, with low litter sizes, low survival rates, or even sterility? Don't worry! Difficulties in breeding gene-edited mice are often related to the following common issues. Let's explore them.

Allergic rhinitis (AR), also known as hay fever, is a common chronic inflammatory disease of the upper respiratory tract characterized by typical symptoms including rhinorrhea, nasal congestion, nasal itching, and recurrent sneezing. It is estimated that over 500 million people worldwide are affected by allergic rhinitis. In China, the prevalence of allergic rhinitis in adults reaches 17.6%, and this number has increased significantly over the past six years.

Today is October 20th, World Osteoporosis Day. When mentioning osteoporosis, many people think of fractures in the elderly caused by calcium deficiency. However, there is a rare disease where patients face the challenge of extremely fragile bones from birth - Osteogenesis Imperfecta (OI), also known as brittle bone disease.